An article published earlier this year describes the use of digoxin-specific antibody fragments for the treatment of suspected Nerium oleander toxicosis in a cat. The article discusses a case of a six year old male cat who presented with lethargy and gastrointestinal signs after possible exposure to Nerium oleander leaves. The cat developed a ventricular arrhythmia that responded positively to the administration of digoxin-specific antibody fragments.
This is the first report to describe the use of digoxin-specific antibody fragments in a cat. Nerium oleander toxicosis is associated with significant morbidity and mortality, and digoxin-specific antibody fragments have been used effectively in humans and animals. The use of digoxin-specific antibody fragments in this case resulted in a rapid response and appeared to be well tolerated.
